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Hall of Famer  star Tony Gwynn has died of cancer at 54.Agent John Boggs said Gwynn died Monday at a hospital in suburban Poway.

Gwynn had been on a medical leave from his job as baseball coach at San Diego State, his alma mater, since late March.

Hall of Famer Tony Gwynn Dead

Gwynn had two operations for cancer in his right cheek between August 2010 and February 2012. The second surgery was complicated, with surgeons removing a facial nerve because it was intertwined with a tumor inside his right cheek. They grafted a nerve from Gwynn’s neck to help him eventually regain facial movement.

Gwynn had said that he believed the cancer was from chewing tobacco.